Provigil for excessive sleepiness

Provigil works well in the treatment of excessive sleepiness

Provigil is a med that promotes wakefulness and it works extremely effective in the treatment of excessive sleepiness which is a complaint mostly from people who are on shift works. There are myriad drugs that work to treat various sleep associated conditions. Drugs like Provigil and its generic variant Modafinil can treat excessive sleepiness conditions that are possibly known to be caused by narcolepsy, sleep apnea and also shift work disorder. Modafinil is believed to be well tolerated in treating excessive sleepiness and also does not affect cardiovascular or other sleep parameters.  If you are someone who is affected by excessive daytime sleepiness and do not know a way out, then reading this blog will be a good choice.

Study on Provigil

A study was conducted among outpatients who received Modafinil in the dosage strengths of 200mg, 300mg, and 400mg or even a placebo once daily for up to twelve weeks. Around 900 patients were receiving treatment with Modafinil while about 50 patients were on placebo. These patients were assessed for adverse events and effects of Modafinil on various health aspects like blood pressure/ heart rates, polysomnography, electrocardiogram intervals and also for clinical laboratory parameters.

Study outcome on Provigil for treating excessive sleepiness

The results that were thus obtained estimated that Modafinil was well tolerated against placebo, though some side effects like a headache, nausea, and infection were noticed. The overall incidence of side effects was known to be similar to that of the three dosage groups of Modafinil. Adverse events that occurred more frequently in the Modafinil group included dry mouth, insomnia, headache, nausea, hypertension, anorexia, nervousness, anxiety, hypertension, and pharyngitis. Among the patients who took Modafinil, around nineteen serious and adverse effects were noticed wherein those in the placebo group, there were about ten serious and adverse events.

Patients who were treated with Modafinil, clinical significance increases in diastolic or systolic blood pressure were observed to be infrequent. Whereas, in the narcolepsy study one patient in the Modafinil group and one in the placebo group were noticed of having a clinically significant increase in heart rate. It was also found that new clinical electrocardiogram abnormalities were rare amongst the Modafinil and placebo group. Also, Modafinil did not interrupt the sleep architecture in any patient as per polysomnography. Yet, clinically significant abnormalities did happen in mean laboratory parameters in about less than one percent of patients who were treated for Modafinil.

Modafinil, therefore, is observed to be well-tolerated and further, it also appears as per research that administration of Modafinil on a daily basis confers a low risk of adverse events or even severe adverse events for that matter. These results make up for a positive ratio for risk-benefit of using Modafinil in the treatment of excessive sleepiness in patients who are on shift work sleep disorder.

Precautions with Provigil

Researchers emphasize that patients who suspect that they might be having a sleep disorder consult a physician immediately. Also, patients can discuss treatment options before treating with medications. Therapies like hypnotics in modern days are considered safe. People taking treatment with medications need to be aware that side effects do arise with any kind of treatment. Medications that are indicated for sleep disorders are also termed to be effective and are considered a safe treatment option, provided the patient is using them properly and under the supervision of a physician.